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Bispecific Antibodies Volume 2051 || Diabodies, Single-Chain Diabodies, and Their Derivatives

✍ Scribed by Kontermann, Roland E.


Book ID
115451817
Publisher
Springer Berlin Heidelberg
Year
2011
Weight
333 KB
Category
Article
ISBN
3642209106

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Recombinant bispecific antibodies for th
✍ Tina Korn; Dirk M. Nettelbeck; Tina Völkel; Rolf Müller; Roland E. Kontermann 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 267 KB

## Abstract We have generated two distinct recombinant bispecific antibody molecules for the retargeting of adenoviral vectors to CEA‐expressing tumour cells. These antibody molecules were produced by combining the antigen‐binding sites of a neutralising anti‐fibre knob scFv (S11) and an anti‐CEA a