Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies
โ Scribed by Guo-Zhong Tao; Ikuo Nakamichi; Nam-On Ku; Jing Wang; Maria Frolkis; Xiaosong Gong; Weimin Zhu; Robert Pytela; M. Bishr Omary
- Book ID
- 118506320
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 929 KB
- Volume
- 312
- Category
- Article
- ISSN
- 0014-4827
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T lymphocytes of 8 patients with ovarian cancer were targeted to the tumor cells using F(ab')2 fragments of a bispecific monoclonal antibody (bsAb), specific for CD3 (a component of the T lymphocyte receptor for antigen) and for the folate receptor MOv I 8 (overexpressed by ovarian carcinoma cells)