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Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases

โœ Scribed by Zhou, Tong; Jope, Richard S.; Song, Ling; Yang, Pingar; Wang, Zheng; Lui, Di


Book ID
109826277
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
204 KB
Volume
5
Category
Article
ISSN
1078-8956

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## Thiols prevent Fas (CD95)-mediated T cell apoptosis by down-regulating membrane Fas expression Thiol antioxidants have been shown to protect cells against apoptosis. Based on the role of Fas in T cell apoptosis, we investigated the effect of thiols on Fas expression. We report that the thiol N-