Bisannelation with Vinylselenoxide: Synthesis of Tricyclo[3.2.1.02,7]octane-6-one and its Congeners
✍ Scribed by Hisahiro Hagiwara; Hitoshi Sakai; Miki Kirita; Takashi Hoshi; Toshio Suzuki; Masayoshi Ando
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 102 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
Reaction of kinetic enolate of a H -substituted cyclohexenone derivatives with vinylselenoxides provided tricyclo[3.2.1.0 2,7 ]octane-6-one derivatives via domino Michael-Michael-substitution protocol.
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In recent years, a number of publlcatlons have appeared in which the tncyclo [3.2.1.02s7] octan-6-one system (1) IS utlllzed in synthetic intermediates as a convement precursor of blcycle [3 2.11 octane and blcyclo [2.2.2] octane systems.' All of these lnvestlgatlons have employed the copper-catalyz
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