Bis-dealkylation of quaternary ammonium salts
โ Scribed by S. Gerszberg; R.Torres Gaona; H. Lopez; J. Comin
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- French
- Weight
- 189 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Several good methods are known for the monodealkylation of quaternary ammonium compounds employing non-reductive nucleophilic agents (l-5). We wish to report here a simple one-step method that leads directly from a quaternary ammonium salt to the acyl derivative of the corresponding secondary amine in fair yields.
๐ SIMILAR VOLUMES
The reactions of thiolate ions derived from thiophenol and homocysteioe with substituted quatemary ammoniom salts result in alkyl tmnsfer from nitrogen to sulfur. A radical mechanism for this tmnsakylation, accounts for the reactivity pattern of the substrate salts. In a model study of the cobalamin
## Abstract The preparation and the physical properties of some quaternary ammonium salts are described.