Spleen cells from C57BU6J mice bearing Ehrlich carcinoma growing as a solid tumor show progressive unresponsiveness to concanavalin A (Con A) and lipopolysaccharide (LPS) mitogens. This is accompanied by striking spleen enlargement with marked hematopoietic activity. Lymphoproliferative assays of no
Biphasic development of splenic suppressor cells in tumor-bearing mice
β Scribed by Q.S. Kapoor
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 340 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0165-2478
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C57BU6J mice immunized with devitalized Ehrlich tumor (ET) cells produce high serum levels of IgM antibodies to E l cell-surface carbohydrates that are critical in the observed resistance against this tumor. However, this response is not found in El-bearing mice at any stage of tumor development. Si
mammalian lymphocytes. However, the indicated respiratory activity of the protozoan mitochondrion does not agree with the idea that the respiratory function of eukaryotic mitochondria depends on the presence of cristae and is proportional to the surface area of the latter [9].