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Biotransformation of the Sympathomimetic Tetraminol in vitro

✍ Scribed by Konstantin Drandarov; Eva Kvasničková; I. M. Hais

Book ID
101645828
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
302 KB
Volume
325
Category
Article
ISSN
0365-6233

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✦ Synopsis

On incubation with the postmitochondrial fraction of the liver homogenate of Biotransformation des Sympathomimetikums Tetraminol in vitro rabbits, guinea-pigs, rats, and mice in the presence of NADPH and oxygen, the u-sympathomimetic rruns ) is preferentially O-demethylated in position 8, yielding metabolite 3. In male rats O-demethylation is stronger than in females.

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Biotransformations of oxaliplatin in rat
Biotransformations of oxaliplatin in rat blood in vitro
✍ Feng R. Luo; Steven D. Wyrick; Stephen G. Chaney 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB

The partitioning and biotransformations of oxaliplatin 1 [trans-l-1,2-diaminocyclohexaneoxalatoplatinum(II)] were investigated in the blood of Wistar male rats in vitro. [3-H]-Oxaliplatin was incubated with rat blood at 37ЊC in 5% CO 2 and the concentrations of all Pt complexes containing the [3-H]-