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Biotransformation of isoflavones by Aspergillus niger as biocatalyst

✍ Scribed by Mitsuo Miyazawa; Koji Takahashi; Hideo Araki

Publisher
Wiley (John Wiley & Sons)
Year
2006
Tongue
English
Weight
109 KB
Volume
81
Category
Article
ISSN
0268-2575

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✦ Synopsis

Abstract

Biotransformation of the isoflavones, 6,7,4′‐trimethoxyisoflavone (1) and 5,7,4′‐trimethoxyisoflavone (2) by Aspergillus niger was investigated. Compound 1 was transformed to 4′‐hydroxy‐6,7‐dimethoxyisoflavone (3) and 2 to 4′‐hydroxy‐5,7‐dimethoxyisoflavone (4). This suggested that 1 and 2 were demethylated at the C‐4′ position with regioselectivity by Aspergillus niger. Copyright © 2006 Society of Chemical Industry

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