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Biotransformation of diclofenac sodium (Voltaren®) in animals and in man

✍ Scribed by Stierlin, H.; Faigle, J. W.; Sallmann, A.; Kung, W.; Richter, W. J.; Kriemler, H.-P.; Alt, K. O.; Winkler, T.


Book ID
121402930
Publisher
Informa plc
Year
1979
Tongue
English
Weight
707 KB
Volume
9
Category
Article
ISSN
0049-8254

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Comparative bioavailability of diclofena
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A phamacokinetic study in man has been made of a new dosage form of diclofenac hydroxyethylpyrrolidine (DIEP); soluble salt packed in sachets was compared with diclofenac sodium as enteric coated tablets. Oral DIEP 2 X 50 mg showed a significant difference in absorption kinetics (ka, lag time and tm