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Biotransformation of alkenes by haloperoxidases: Regiospecific bromohydrin formation from cinnamyl substrates

✍ Scribed by Philip Coughlin; Stanley Roberts; Cliff Rush; Andrew Willetts


Publisher
Springer Netherlands
Year
1993
Tongue
English
Weight
367 KB
Volume
15
Category
Article
ISSN
0141-5492

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✦ Synopsis


A study of bromohydrin formation from some cinnamyl substrates by the heme-dependent chloroperoxidase from Caldariomyces fumago has identified differences in the regio-and diastereospecificity of this enzyme relative to chemical hydrobromination. Diastereospecificity of bromohydrin formation from (E)-4-phenyl-buten-2-01 by the vanadium-dependent bromoperoxidase from the alga Corallina officinalis is similar to that of the fungal enzyme but significantly different to the equivalent chemical reaction.