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Biotransformation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Lung Tissue from Mouse, Rat, Hamster, and Man

โœ Scribed by Richter, Elmar; Engl, Johannes; Friesenegger, Susanne; Tricker, Anthony R.


Book ID
125856761
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
517 KB
Volume
22
Category
Article
ISSN
0893-228X

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The expression profile of adenoma induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice was compared with that of normal lung tissue by suppression subtractive hybridization (SSH). The mRNAs of surfactant-associated protein A (SP-A) and lysozyme showed characteristically higher