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Biotin deficiency in mice is associated with decreased serum availability of insulin-like growth factor-I

✍ Scribed by Armida Báez-Saldaña; Gabriel Gutiérrez-Ospina; Jesús Chimal-Monroy; Cristina Fernandez-Mejia; Rafael Saavedra


Book ID
106066505
Publisher
Springer
Year
2009
Tongue
English
Weight
450 KB
Volume
48
Category
Article
ISSN
1436-6207

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The present report investigates the cellular mechanisms involved in the regulation of cell proliferation by insulin and insulin-like growth factor-I (IGF-I) in the developing inner ear. The results show that insulin and IGF-I stimulate cell proliferation in the otic vesicle. This effect is associate