A two-generation reproductive toxicity study of methyl tertiary-butyl ether (MTBE) was conducted in Sprague-Dawley rats. Twenty-five rats of each sex (F 0 ) were exposed by inhalation to 0, 400, 3000 or 8000 ppm MTBE vapor, 6 h a day for 10 weeks prior to mating. Parental animals were then mated wit
Biotic and Abiotic Transformations of Methyl tertiary Butyl Ether (MTBE) * (6 pp)
โ Scribed by Axel Fischer; Claudia Oehm; Michael Selle; Peter Werner
- Book ID
- 111725932
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 408 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0944-1344
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Pregnant CD-1 mice (30 per group) and female New Zealand White rabbits (15 per group) were exposed by inhalation to 0, 1000, 4000 and 8000 ppm methyl tertiary-butyl ether (MTBE) vapor for 6 h a day during gestational days (GD) 6-15 and 6-18, respectively. Maternal body weights, clinical observations
Oncogenicity studies of methyl tertiary-butyl ether (MTBE) vapor were conducted in CD-1 mice and Fischer 344 rats. Fifty animals of each sex per species per group were exposed for 6 h a day, 5 days per week to 0 (control), 400, 3000 and 8000 ppm MTBE vapor in air for 18 months (mice) and 24 months (