Biosynthetic methods for incorporating positron-emitting radionuclides into compounds of biomedical interest

✍ Scribed by Alan S. Gelbard

• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: French
• Weight: 427 KB
• Volume: 18
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580180703

✦ Synopsis

Abstract

The progress that has been made in incorporating the short‐lived, positron‐emitting isotopes N‐13 and C‐11, into biologically active compounds by biosynthetic means is reviewed. These methods include the use of whole cells or plant leaves to carry out a sequence of metabolic reactions, such as nitrogen fixation or photosynthesis, and the use of purified enzymes to catalyze specific chemical reactions, to form the labeled compounds.