✦ LIBER ✦

Biosynthetic capacities of actinomycetes. 5. Dioxolides, novel secondary metabolites from Streptomyces tendae

✍ Scribed by Sabine Blum; Ingrid Groth; Jürgen Rohr; Dr. Hans-Peter Fiedler

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 385 KB
Volume: 36
Category: Article
ISSN: 0233-111X
DOI: 10.1002/jobm.3620360105

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Dioxolides, a novel class of secondary metabolites were detected by a HPLC‐diode array screening technique in the culture filtrate of Streptomyces tendae Tü 4042. The compounds show no biological activity against Gram‐positive and Gram‐negative bacteria, yeasts and fungi. Besides dioxolides, which consist of an unusual substituted dioxolane ring, anhydroshikimate and para‐hydrobenzamide were detected by this technique. Both compounds were not yet described as natural products.

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