✦ LIBER ✦
Biosynthesis of the pyrrolidine ring of nicotine : Feeding experiments with N15-labeled ornithine-2-C14
✍ Scribed by Edward Leete; Eduardo G. Gros; Terry J. Gilbertson
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- French
- Weight
- 261 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
When ornithine-2-C" was fed to intact tobacco plants radioactive nicotine (VII) was obtained in which essentially all the activity was located at C2 and C5 of the pyrrolidine ring and was equally divided between these positions (1,2). A similar result was obtained when glutamic acid-2-C l4 (3,4) or proline-2-C14 (5) were fed to Nlcotiana plants, although these amino acids were less efficient precursors of nicotine than ornithine. Putrescine-l,4-C14 (III) was also found to be a