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Biosynthesis of the precursor of a soluble human insulin receptor ectodomain in insect Sf9 cells infected with a recombinant baculovirus

✍ Scribed by Janice F. Sissom; Leland Ellis

Book ID
115764603
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
901 KB
Volume
177
Category
Article
ISSN
0006-291X

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The insulin receptor is an integral transmembrane glycoprotein comprised of two alpha-(approximately 135 kDa) and two beta-(approximately 95 kDa) subunits, which is synthesized as a single polypeptide chain precursor (alpha beta). The primary sequence of the human insulin receptor (hIR) protein, ded