We have been able to define partially the biosynthetic pathway of camptothecin (lJ based on the results of feeding experiments with 13c 14
Biosynthesis of the dimeric indole alkaloids. II. Catharanthine as a precursor of vincaleukoblastine.
β Scribed by S.B. Hassam; C.R. Hutchinson
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 227 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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Our recently synthesized' pentacyclic ester lactam(l) represents a central intermediate for preparing, with proper structural variations, reserpinoid and yohimbinoid molecules2 since itsD/E ring junction reduces cis 1 while maintaining an epimerizable C20 hydrogen for possible conversion toD/E trans
## Abstract For Abstract see ChemInform Abstract in Full Text.