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Biosynthesis of Natural Products on Modular Peptide Synthetases

✍ Scribed by Sascha Doekel; Mohamed A. Marahiel

Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
449 KB
Volume
3
Category
Article
ISSN
1096-7176

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πŸ“œ SIMILAR VOLUMES

Hybrid Peptide–Polyketide Natural Produc
Hybrid Peptide–Polyketide Natural Products: Biosynthesis and Prospects toward Engineering Novel Molecules
✍ Liangcheng Du; CΓ©sar SΓ‘nchez; Ben Shen πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 450 KB

The structural and catalytic similarities between modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) inspired us to search for hybrid NRPS-PKS systems. By examining the biochemical and genetic data known to date for the biosynthesis of hybrid peptide-polyketide natural prod