## Dedicated to Professor Meinhart H. Zenk on the occasion of his 70th birthday The deadly poisonous toadstool Cortinarius orellanus (Fr.) Fr. [1] causes an irreversible loss of kidney function within one to two weeks after ingestion. [2] The toxicity of this fungus was recognized nearly 50 years
Biosynthesis of Moniliformin, A Fungal Toxin with Cyclobutanedione Structure
β Scribed by Prof. Dr. Burchard Franck; Dr. Gerhard Breipohl
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 329 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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A novel highly cytotoxic metabolite, apicularen A (1), was isolated in a screening of the myxobacterial genus Chondromyces. The structure of 1 is characterized by a salicylic acid residue as part of a 10-membered lactone, which bears an acylenamine side chain. Compound 1 is an inhibitor of the proli