Biosynthesis of disialylated β-d-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-β-d-glucopyranosyl oligosaccharide chains. Identification of a β-d-galactoside α-(2→3)- and a 2-acetamido-2-deoxy-β-d-glucoside α-(2→6)-sialyltransferase in regenerating rat liver and other tissues
✍ Scribed by Hans T. de Heij; Piet L. Koppen; Dirk H. van den Eijnden
- Book ID
- 108309085
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 1016 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0008-6215
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Treatment of benzyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside with 4-methoxybenzaldehyde dimethyl acetal in N,N-dimethylformamide in the presence of 4-toluenesulfonic acid afforded the 4,6-O-(4-methoxybenzylidene) acetal, which was glycosylated with 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosy
Condensation of benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-galactopyranoside with 2,3,4-tri-o-acetyl-a-D-fucopyranosyl bromide in 1: 1 nitromethane-benzene, in the presence of powdered mercuric cyanide, afforded benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-0-(2,3,4-tri-O-acetyl-P-D-fucopyran