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Biosynthesis of clavulanic acid: origin of the C3 unit

โœ Scribed by Townsend, Craig A.; Ho, Meng Fei


Book ID
118040208
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
378 KB
Volume
107
Category
Article
ISSN
0002-7863

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A primary isotope effect was utilised in an in vitro study to allow the isolation and characterisation of an intermed& between proclavaminic acid and clavaminic acid, in clavulanic acid biosynthesis.1 Clavulanic acid (l), a medicinally important bicyclic ~lactam produced by Srreptomyces ckzvuligerus