The use of amphotericin B to detect inhi
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Monty Krieger
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Article
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1983
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Elsevier Science
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English
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Pores formed in the membranes of animal cells by complexes of sterols and the polyene antibiotic amphotericin B can efficiently kill the cells. Thus, in the absence of exogenous sources of cholesterol, inhibitors of enzymes in the cholesterol biosynthetic pathway render cells resistant to amphoteric