Biosynthesis of 24β-alkyl-Δ25-sterols in hairy roots of Ajuga reptans var. atropurpurea

Mechanism of clerosterol biosynthesis in

Mechanism of clerosterol biosynthesis in Ajuga hairy roots: stereochemistry of C-28 methylation of 24-methylene sterol

✍ Takeshi Koami; Kiyoshi Ohyama; Yoshinori Fujimoto 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 82 KB

Biosynthesis of clerosterol, (24S)-ethylcholesta-5,25-dien-3b-ol (1), involves transfer of the methyl group from S-adenosylmethionine to the C-28 position of a 24-methylene-sterol precursor. The resulting C-24 cationic species undergoes migration of hydrogen from C-25 to C-24, followed by deprotonat