Biosynthesis of 20-hydroxyecdysone in Ajuga hairy roots: Hydrogen migration from C-6 to C-5 during cis-A/B ring formation

✍ Scribed by Yoshinori Fujimoto; Tetsuo Kushiro; Kinya Nakamura

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 187 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00432-2

✦ Synopsis

Feeding of deuterium labeled cholesterols including [6-2H]cholesterol and [3ct,6-2H2 Icholesterol to hairy roots of Ajuga reptans var. atropurpurea followed by 2H-NMR analysis of the biosynthesized 20-hydroxyecdysone revealed that most of the deuterium atom located at C-6 of cholesterol migrated to the C-5 position of 20-hydraxyecdysone.