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Biosynthesis and NMR-studies of a double transmembrane domain from the Y4 receptor, a human GPCR

✍ Scribed by Chao Zou; Fred Naider; Oliver Zerbe

Book ID: 106401586
Publisher: Springer Netherlands
Year: 2008
Tongue: English
Weight: 492 KB
Volume: 42
Category: Article
ISSN: 0925-2738
DOI: 10.1007/s10858-008-9281-z

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## Abstract Fragments of G protein‐coupled receptors (GPCRs) are widely used as models to investigate these polytopic integral–membrane, signal‐transducing molecules, but have proven difficult to prepare in quantities necessary for NMR analyses. We report on the biosynthesis of two double transmemb