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Biosensors for DNA sequence detection

✍ Scribed by Wenonah Vercoutere; Mark Akeson

Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
315 KB
Volume
6
Category
Article
ISSN
1367-5931

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✦ Synopsis

DNA biosensors are being developed as alternatives to conventional DNA microarrays. These devices couple signal transduction directly to sequence recognition. Some of the most sensitive and functional technologies use fibre optics or electrochemical sensors in combination with DNA hybridization. In a shift from sequence recognition by hybridization, two emerging single-molecule techniques read sequence composition using zero-mode waveguides or electrical impedance in nanoscale pores.

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DNA Biosensor Prepared by Electrodeposit
DNA Biosensor Prepared by Electrodeposited Pt-nanoparticles for the Detection of Specific Deoxyribonucleic Acid Sequence in Genetically Modified Soybean
✍ Mao-Qing WANG; Xiao-Yan DU; li-Yan LIU; Qian SUN; Xian-Chen JIANG πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 Chinese βš– 284 KB

DNA biosensors were prepared by electrodepositing platinum nanoparticles (Pt-nano) on the surface of a glassy carbon electrode (GCE). A 19-mer ssDNA of promoter 35S, which was specific to most inserted sequences in genetically modified food, was immobilized on the Pt nanoparticle-deposited GC electr