✦ LIBER ✦

Biosensor Analysis of Drug–Target Interactions: Direct and Competitive Binding Assays for Investigation of Interactions between Thrombin and Thrombin Inhibitors: Volume 278, Number 1 (2000), pages 1–13

✍ Scribed by Robert Karlsson; Mari Kullman-Magnusson; Markku D. Hämäläinen; Annika Remaeus; Karl Andersson; Peter Borg; Erika Gyzander; Johanna Deinum

Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 13 KB
Volume: 291
Category: Article
ISSN: 0003-2697
DOI: 10.1006/abio.2001.5026

No coin nor oath required. For personal study only.

✦ Synopsis

On page 3 under Materials and Methods, column 1, a description of the method for stabilization of immobilized target with a second injection of EDC/NHS did not include the reference "P-O. Markgren (personal communication).

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Biosensor Analysis of Drug–Target Interactions: Direct and Competitive Binding Assays for Investigation of Interactions between Thrombin and Thrombin Inhibitors

✍ Robert Karlsson; Mari Kullman-Magnusson; Markku D. Hämäläinen; Annika Remaeus; K 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 202 KB

The sensitivity of BIACORE technology is sufficient for detection and characterization of binding events involving low-molecular-weight compounds and their immobilized protein targets. The technology requires no labeling and provides information on the stability of the compound/target complex with a