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Bioreducible polycationic micelles for in vitro gene delivery

โœ Scribed by Ya-Nan Xu; Lei Liu; Xiao Ji; Shi-Wen Huang; Ren-Xi Zhuo


Book ID
113694786
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
501 KB
Volume
152
Category
Article
ISSN
0168-3659

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Biodegradable polyphosphoester micelles
โœ Jie Wen; Hai-Quan Mao; Weiping Li; Kevin Y. Lin; Kam W. Leong ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 469 KB

A new biodegradable polyphosphoester, poly[[(cholesteryl oxocarbonylamido ethyl) methyl bis(ethylene) ammonium iodide] ethyl phosphate] (PCEP) was synthesized and investigated for gene delivery. Carrying a positive charge in its backbone and a lipophilic cholesterol structure in the side chain, PCEP