Biophysical models of ciliary activity: Gaussian frequency distributions

✍ Scribed by P. Thyberg; R. Rigler; K. Svartengren; L. G. Wiman

• Book ID: 104654256
• Publisher: Springer
• Year: 1990
• Tongue: English
• Weight: 630 KB
• Volume: 18
• Category: Article
• ISSN: 1432-1017
• DOI: 10.1007/bf00183267

✦ Synopsis

A model of a freely rotating exended scatterer is proposed to describe light scattering from beating cilia. Gaussian rotation frequency distributions, characterized by a mean angular frequency and a standard deviation, are introduced in order to simulate intensity autocorrelation functions and to fit the model to experimental data. Thus the ciliary beats are characterized by a mean beat frequency and a standard deviation of the beat frequency distribution. The standard deviation influences the damping of the intensity autocorrelation function of light scattered from cilia. The calculated intensity autocorrelation function shows a more prominent oscillating behaviour the smaller the standard deviation of the beat frequency. The validity of the model is supported by experimental data in two ways: 1) The model fits very well to experimental data in computer evaluations, 2) Neither the model nor information obtained from measurements are dependent on the measuring angle.