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Biophysical Characterization of a Novel KCNJ2 Mutation Associated with Andersen-Tawil Syndrome and CPVT Mimicry

✍ Scribed by Barajas-Martinez, Hector; Hu, Dan; Ontiveros, Gustavo; Caceres, Gabriel; Burashnikov, Elena; Scaglione, Jorge; Antzelevitch, Charles


Book ID
122130783
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
60 KB
Volume
96
Category
Article
ISSN
0006-3495

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Long QT (LQT) syndrome is a potentially life-threatening disorder, characterized by a distinct cardiac arrhythmia known as torsades de pointes. Mutations within a number of genes linked to the familial form, including that coding for a cardiac potassium channel called KCNH2 (HERG), have been describ