Bioorganotin chemistry: situs and stereoselectivity in the reaction of cyclohexyltriphenyltin with a cytochrome P-450 dependent monooxygenase enzyme system

✍ Scribed by Richard H. Fish; John E. Casida; Ella C. Kimmel

• Book ID: 104235577
• Publisher: Elsevier Science
• Year: 1977
• Tongue: French
• Weight: 287 KB
• Volume: 18
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)83280-9

✦ Synopsis

One of the most interesting and important biological reactions is the cytochrome P-450 dependent monooyygenase enzyme reaction with organic and organometallic substrates la-d . The reaction involves a Heme-Iron-Monooxygen complex2, which converts carbon-hydrogen bonds ti carbon-hydroyyl bonds. While several investigations have been concerned with the stereochemistry of this reaction 3 , few have concentrated on the cyclohexyl ring system ka,b . To our