Bioorganic and Medicinal Chemistry of Fluorine || Effects of Fluorine Substitution on Biological Properties

✍ Scribed by Bgu, Jean-Pierre; Bonnet-Delpon, Danile

• Book ID: 120483699
• Publisher: John Wiley & Sons, Inc.
• Year: 2008
• Tongue: English
• Weight: 535 KB
• Edition: 1
• Category: Article
• ISBN: 0470278307
• DOI: 10.1002/9780470281895.ch3

✦ Synopsis

The Discovery Of Fluorouracil, Fluorocorticoids, And Fluoroquinolones Has Led To Expanded Interest In The Usage Of Fluorine In Chemistry. The First Comprehensive Reference Dedicated To Detailing The Influence Of Fluorine On The Structural Properties Of A Molecule And On A Molecule's Biological Behavior, Bioorganic And Medicinal Chemistry Of Fluorine Uses Examples Of Fluorinated Drugs To Provide A Thorough Overview Of The Role Of Fluorine In Pharmaceutical Science And Development. Complete With References For Further Study, This The Premier Resource On Fluorine For Pharmaceutical And Medicinal Chemists In Academia Industry, Researchers In Organic Chemistry And Biochemistry, And Advanced Students And Educators In Pharmaceutical And Medicinal Chemistry, Biochemistry, And Organic Chemistry.--jacket. General Remarks On Structural, Physical, And Chemical Properties Of Fluorinated Compounds -- Overview On The Preparation Of Fluorinated Compounds -- Effects Of Fluorine Substitution On Biological Properties -- Fluorinated Analogues Of Natural Products -- Fluorinated Derivatives Of ?-amino Acids And Proteins -- Saccharidic Fluorinated Derivatives -- Inhibition Of Enzymes By Fluorinated Compounds -- Fluorinated Drugs. Jean-pierre Bégué, Danièle Bonnet-delpon ; Translated From French By Julien Legros. Translated From The French. Includes Bibliographic References And Index.