## Abstract The cationic cyclization of 2‐[6‐(__m__‐methoxyphenyl)‐(__E__)‐3‐hexenyl]‐3,5‐dimethyl‐2‐cyclopentenol (**3**) was investigated. Exclusive formation of 1‐ and 3‐methoxy‐15α,17‐dimethyl‐1,3,5(10), 13(17)‐gonatetraene (**4** and **5**) was observed, indicating complete stereoselectivity i
✦ LIBER ✦
Biomimetic total synthesis of steroids III: Stereoselective synthesis of 11α-methyl-19-norsteroids
✍ Scribed by M. B. Groen; F. J. Zeelen
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 565 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0165-0513
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## Abstract Cationic cyclization of 2‐[6‐(3‐methoxyphenyl)‐(Z)‐3‐hexenyl]‐3‐methyl‐2‐cyclopentenol (7a) produced 1‐ and 3‐methoxy‐17‐methyl‐8α‐gona‐1,3,5(10),13(17)‐tetraene (**8a** and **9a**) with complete stereospecificity. Cyclization of similar substrates with an alkyl substituent in the appro