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Biomimetic synthesis and stereostructure of K-13, a novel inhibitor of angiotensin I converting enzyme

✍ Scribed by Shigeru Nishiyama; Yoshikazu Suzuki; Shosuke Yamamura

Book ID
108382676
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
251 KB
Volume
30
Category
Article
ISSN
0040-4039

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## Abstract We prepared the angiotensin converting enzyme (ACE) inhibitor N‐[1(S)‐carboxy‐3‐(4′‐^3^H)carboxanilidopropyl]‐L‐Ala‐L‐Pro (^3^H‐RAC‐X‐65). The triflate of D‐(+)‐lactic acid benzyl ester was reacted with N′‐(4‐iodophenyl)‐L‐glutamine methyl ester. The benzyl ester was removed with HF, an