Biomimetic models of lactate dehydrogenase
✍ Scribed by Jiří Krechl; Svatava Smrčková
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 207 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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Molecular modeling was employed for the design of a biomimetic chimeric ligand for L-lactate dehydrogenase (LDH). This ligand is an anthraquinone monochlorotriazinyl dye comprising two moieties: (a) the ketocarboxyl biomimetic moiety, 2-(4-aminophenyl)ethyloxamic acid, linked on the monochlorotriazi
Lactate dehydrogenase ## Biochemistry and fwnction of lactate dehydrogenase Lactate dehydrogenase (EC 1.1.1.27, L-lactate: NAD+ oxidoreductase) is a n ubiquitous enzyme among vertebrate organisms', and carries out a straightforward equilibration of: NAD' + lactate + NADH + pyruvate Lactate dehydr