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Biomedical Engineering Systems and Technologies: Third International Joint Conference, BIOSTEC 2010, Valencia, Spain, January 20-23, 2010, Revised ... in Computer and Information Science, 127)

✍ Scribed by Ana Fred (editor), Joaquim Filipe (editor), Hugo Gamboa (editor)


Publisher
Springer
Year
2011
Tongue
English
Leaves
413
Category
Library

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✦ Synopsis


This book constitutes the thoroughly refereed post-conference proceedings of the Third International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2010, held in Valencia, Spain, in January 2010. The 30 revised full papers presented together with 1 invited lecture were carefully reviewed and selected from a total of 410 submissions in two rounds of reviewing and improvement. The papers cover a wide range of topics and are organized in four general topical sections on healthinf, biodevices, biosignals, and bioinformatics.

✦ Table of Contents


Title
Preface
Organization
Table of Contents
Invited Papers
Personal Health:The New Paradigm to Make Sustainable the Health Care System
Introduction
Telemedicine and Health
New Paradigm for Health Care Systems
Disruptive Innovation
Chronic Disease Challenge
Personal Health Systems
Information and Communication Technologies (ICT)
RFID
Sensors
Internet 2.0
Electronic Health Records
Ambient Intelligence
Conclusions
References
Part I Health Informatics
Registration and Fusion Techniques for Medical Images: Demonstration and Evaluation
Introduction
System Architecture
Data Collection and Data Management Subsystem
Medical Data Preprocessing Subsystem
Medical Data Alignment Subsystem
Medical Data Fusion Subsystem
Graphical Interface Subsystem
Working Environment
Pilot Scenario
Quantitative Analysis of Registration Results
Three-Dimensional Display of Anatomic Structures
Conclusions
References
Prediction of Pancreatic Cancer Survival through Automated Selection of Predictive Models
Introduction
Machine Learning
Classical Meta-learning
Proposed Automated Model Selection Meta-learning Approach
Plan of the Paper
Pancreatic Cancer Clinical Datasets
Pre-operative and All-attributes Predictive Attribute Sets
Prediction Target Attribute
Summary of Datasets Considered
Learning to Predict the Best Performing Model
Model Selection Meta-learning for Prediction
Training the Model Selection Metalearner
Evaluation
Preprocessing and Predictive Techniques Used
Experimental Protocol
Results and Discussion
Conclusions
References
Web of Active Documents: An Architecture for Flexible Electronic Patient Records
Motivations and Background
Webs of Active Documents
Datoms, Didgets and Templates
Mechanisms in the WOAD Framework
Interaction with the WOAD Architecture
Conclusions and Future Work
References
A Personalization Environment for Multi-version Clinical Guidelines
Introduction
Versioning of Clinical Guidelines
Temporal Versioning
Semantic Versioning
An XML Data Model for Multi-version Guidelines
Manipulation and Retrieval Operations
Prototype Implementation
Conclusions and Future Work
References
Dynamic Routing Using Health Information Policy with Apache Camel
Introduction
Background
Message-Oriented Middleware (MOM)
Enterprise Integration Patterns
Apache Camel
Health Information Policy
Implementing Information Policy
Routing Based on Medical Context
Enriching Messages with Medical Context
Test Scenario
Conclusions
References
A Personal Health Record System for Emergency Case Management
Introduction
Related Work
Motivating Scenario
System Architecture
Security Architecture
Access Control Policies
Context Information Management
Implementation Issues
Concluding Remarks
References
A Method for Representing and Querying Temporal Information in OWL
Introduction
Background
Temporal Model
Temporal Querying
Basic Temporal Queries: Allen’s Operators
More Advanced Temporal Queries: Grouping and Aggregation
More Advanced Temporal Queries: Temporal Collections
Conclusions
References
Designing a Telemedical System for Cardiac Exercise Rehabilitation
Introduction
Rehabilitation after Cardiac Events
User Centered Design of Telemedicine Applications
Technical Requirements of Telemedicine Applications
Related Work
Background: OSAmI-D
A User Study
Interview Lead through
The Current Setting
Results
User Interface Design
Mockups
Conclusions
References
A Value and Model Driven Method for Patient Oriented KPI Design in Health Care
Introduction
Related Work
Method for Value Based KPI Identification
Task 1: Develop Value Model
Task 2: Generate Technical KPIs
Task 3: Generate Functional KPIs
Method Application
Concluding Remarks
References
Part II Biomedical Electronics and Devices
Encapsulated Multi-vesicle Assemblies of Programmable Architecture: Towards Personalized Healthcare
Introduction
Material and Methods
Results
Discussion
Encapsulation
Compartmentalization
Composition Control
Conclusions
References
Adaptive RBF-HMM Bi-Stage Classifier Applied to Brain Computer Interface
Introduction
Experimental Procedure
Flow of Activities in the Experimental Process
Electrode Position
Description of Cognitive Activities
Description of the Classifier
Introduction
Preprocessing
Training of the Neural Network
Description of Hidden Markov Models
Training of the Hidden Markov Models
Results
Evaluation of the Learning Capability
Evaluation of the Generalisation Capability
Discussion
Conclusions
References
Thermal Characteristics of Microcantilever Biosensors
Introduction
Theory and Numerical Analysis
Numerical Analysis
Results and Discussion
Conclusions
References
Prosodic Speech Restoration Device: Glottal Excitation Restoration Using a Multi-resolution Approach
Introduction
Speech Rehabilitation for Alaryngeal Speakers
Characteristics of Pathological Speech
Multi-resolution Voice Restoration
Method
Long-Term Pitch Estimation
Middle-Term Pitch Restoration
Short-Term Pitch Restoration
Results
Conclusions
References
An Investigation on ALD Thin Film Evanescent Waveguide Sensor for Biomedical Application
Introduction
Fabrication
Buckling of Thin Film
Front Side Fabrication
Propagation Losses
Free Standing Structure
Free Standing Processing
New Structure Definition
Conclusions
References
Part III Bio-inspired Systems and Signal Processing
Probabilistic Patient Monitoring with Multivariate, Multimodal Extreme Value Theory
Introduction
Existing Patient Monitors
Intelligent Patient Monitoring
Contributions in This Paper
Classical Extreme Value Theory
Redefining ``Extrema''
Density Estimation
Method
Introduction
Detail of Method
Novelty Score Assignment
Validation on Simulated Data
Application to Vital-sign Data
Discussion
Conclusions
Future Work
Downloadable Content
References
Weighted SVMs and Feature Relevance Assessment in Supervised Heart Beat Classification
Introduction
State of the Art
Theoretical Background
Weighted SVM Classifier
Hermite Basis Functions
Higher Order Statistics
ECG Database and Preprocessing
Feature Extraction
Experiments and Results
Feature Relevance Assessment
Peformance Evaluation
Conclusions
References
The Investigation and Clinical Significance of Resonance in the Heart Rate and Vascular Tone Baroreflexes
Introduction
0.1 Hz Resonance in the CVS
Prior Studies: 0.1 Hz Resonance in the CVS Caused by Respiration
Study 1: 0.1 Hz Resonance in the CVS Caused by Rhythmical Muscle Tension
Study 2: 0.1 Hz Resonance in the CVS Caused by Emotional Pictures Cues
0.03 Hz Resonance in the CVS
Study 1: 0.03 Hz Resonance in the CVS Caused by Aversive Sound
Study 2: 0.03 Hz Resonance in the CVS Caused by Negative Emotional Pictures
Discussion
Conclusions
References
Glottal Inverse Filtering of Speech Based on Homomorphic Prediction: A Cepstrum-Based Algorithm Not Requiring Prior Detection of Either Pitch or Glottal Closure
Introduction
Simulated Voice Signals
Simulation Model
Characteristics of Simulated Glottal Signals
Inverse Filtering Algorithms
Iterative Adaptive Inverse Filtering (IAIF)
Homomorphic Prediction (HoP)
Results
Conclusions
References
Texture Discrimination with Artificial Whiskers in the Robot-Rat Psikharpax
Introduction
System Description
Texture Discrimination
Feature Extraction
Fixed Head Experiment
Mobile Robot Experimentation
Discussion
Conclusions
References
Heart Rate Variability and the Acceleration Plethysmogram Signals Measured at Rest
Introduction
Data
Methodology
Detection of a-Waves
HRV Analysis
Results
Conclusions
References
Emotional Face Perception in Healthy Subjects and Parkinson's Disease: An Effective Connectivity Study
Introduction
Methods
Effective Connectivity Analysis
Results
Discussion
Conclusions
References
Biometric Authentication with Electroencephalograms: Evaluation of Its Suitability Using Visual Evoked Potentials
Introduction
Electroencephalograms
Visual Evoked Potentials (VEPs)
Related Work
An EEG-Based Authentication System Using VEP
Personal Classifiers
Authentication Process
Description of the Data Set
Feature Array Extraction
The Feature Classifier
Experimentation
Overall Evaluation Results
Evaluation of Individual Classifiers
Open Issue: Constancy
Conclusions
References
Part IV Bioinformatics
Reconstructing the Phylogenetic Relationships of the Cyclophyllidean Cestodes: A Case Study Using ITS2 rDNA and Sequence-Structure Alignment
Introduction
Materials and Methods
Sequence Alignments and Molecular Phylogenetic Analysis
Bayeasian Phylogenetic Analysis
ITS2 Secondary Structure Prediction and Sequence Structure Alignment Footnotes
Results
Neighbour-Joining (NJ) and Maximum Parsimony (MP) Trees
Bayesian Phylogeny
Secondary Structure Analysis and GC Content
Discussion
Conclusions
References
ReHap: A Framework for Single Individual Haplotyping from Next-Generation Sequencing Data
Introduction
Functionalities
Algorithms Supported
Algorithms Evaluation
Experiments
Conclusions
References
Inference of Large Phylogenies Using Neighbour-Joining
Introduction
Methods
The Neighbour-Joining Method
RapidNJ
Reducing the Memory Consumption of RapidNJ
An I/O Algorithm for Building Very Large Trees
Improving the Search Heuristic
Experiments
Experimental Setup
Results and Discussion
Conclusions
References
Prediction of Minimum Free Energy Structure for Simple Non-standard Pseudoknot
Introduction
Simple Non-standard Pseudoknots
Problem Definition
Prediction Algorithm
Subregion in Simple Non-standard Pseudoknot
Dynamic Programming Algorithm
Conclusions
References
Intra- and Inter-Molecular Coevolution: The Case of HIV1 Protease and Reverse Transcriptase
Introduction
Materials and Methods
Sequence Data
Information Theoretical Measures on (Co-)evolution
Results
Comparing Intra- and Inter-Protein Co-evolution of Residues
Co-evolution between Residues in the PR and the RT?
Discussion and Summary
References
Structured Output Prediction of Novel Enzyme Function with Reaction Kernels
Introduction
Enzyme Function Prediction
Annotation Transfer Approaches
Machine Learning Approaches
Structured Output Learning
Joint Kernels
Learning Task
Preimage Problem
Kernels for Chemical Reactions
Kernels for Molecule Graphs
Sum-of-Reactants Kernel
Reactant-Matching Kernels
Experiments
Data
Compared Methods
Measure of Success
Results
Discussion and Future Work
References
A Parallel Algorithm for Counting Subgraphs in Complex Networks
Introduction
Preliminaries
Network Terminology
Subgraph Census
Related Work
Parallel Algorithms
Core Sequential Unit
Initial Parallel Approaches
Adaptive Parallel Enumeration
Results
Conclusions
References
Efficient Searching for Motifs in DNA Sequences Using Position Weight Matrices
Introduction
Position Weight Matrices
Algorithm
Algorithm Performance
Space Performance
Time Performance
Discussion
References
Author Index


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