Biomedical Composites: Perspectives and Applications (Materials Horizons: From Nature to Nanomaterials)

✍ Scribed by Amit Kumar Nayak (editor), Md Saquib Hasnain (editor)

• Publisher: Springer
• Year: 2021
• Tongue: English
• Leaves: 227
• Edition: 1st ed. 2021
• Category: Library

✦ Synopsis

This book provides an overview of biocomposite chemistry, chemical modifications, characterization and applications in biomedicine, with emphasis on recent advances in the field. Authored by experts, the chapters discuss the design, development and selection of biomedical composites for a particular therapeutic application, as well as providing insight into the regulatory and clinical aspects of biomedical composite use. While this book is primarily intended for scientists from the fields of medical, pharmaceutical, biotechnological and biomedical engineering, it is also useful as an advanced text for students and research scholars.

✦ Table of Contents

Preface
Contents
About the Editors
Biomedical Applications of Nanosilicate Composites
1 Biomedical Composites: Definition and Applications
2 Clay Minerals and Nanosilicates
3 Nanosilicate Composites in Tissue Engineering and Regenerative Medicine
4 Nanosilicate Composites in Dental Research
5 Nanosilicate Composites in Drug Delivery Research
6 Nanosilicate Composites in Wound Healing and Hemostasis
7 Conclusions
References
Polysaccharide-Based Composites for Biomedical Applications
1 Introduction
2 Natural Polysaccharides
3 Natural Polysaccharides-Based Composites Applications
3.1 Drug Delivery
3.2 Bionsensors
3.3 Tissue Engineering
3.4 Wound Dressing
4 Conclusions
References
Biomedical Nanocomposites
1 Introduction
2 Nanocomposites
3 Nanocomposites for Biomedical Applications
3.1 Drug Delivery
3.2 Gene Delivery
3.3 Antimicrobials
3.4 Tissue Regeneration
3.5 Prosthesis
3.6 Dentistry
3.7 Wound Healing
3.8 Bioimaging and Biosensor
4 Conclusion
References
Antimicrobial Nanocomposites
1 Introduction
2 Application of Nanocomposites as Antimicrobial Agents
3 Application of Antimicrobial Nanocomposites in Food Packaging
4 Application of Antimicrobial Nanocomposites in Water Treatment
5 Antimicrobial Nanocomposites Are Used as Anticancer Agents
6 Application of Antimicrobial Nanocomposites in Dental Application
7 Conclusion
References
Potential Application of Silver Nanocomposites for Antimicrobial Activity
1 Introduction
1.1 Pathogenic Strains for Infection
1.2 Global Statistics and Market Value of Bacterial Infections
1.3 Conventional Treatment Strategies for Bacterial Infections
1.4 Limitations to Current Treatment Strategies
1.5 Nanotechnology and Its Applications
2 Historical Background of Silver
3 Synthesis and Characterization of Silver Nanocomposites
4 Role of Shape, Size and Charge of Silver Nanocomposites on Antimicrobial Activity
5 Silver Nanocomposites and Their Antimicrobial Activity
5.1 Graphene Silver Nanocomposites
5.2 Chitosan-Based Silver Nanocomposites
5.3 Nitroprusside-Based Silver Nanocomposites
5.4 Prussian Blue-Based Silver Nanocomposites
5.5 Cellulose-Based Silver Nanocomposites
5.6 Synthetic Polymer-Based Silver Nanocomposites
5.7 Biosynthesized Silver Nanocomposites
6 Antimicrobial Activity of Silver Nanocomposites: Mechanistic Approach
7 Commercial Applications of Antibacterial Activity of Silver Nanocomposites
7.1 Wound Healing
7.2 Medical Devices
7.3 Tissue Engineering
7.4 Other applications
8 Toxicity of Silver Nanocomposites
9 Future Perspectives and Challenges
10 Conclusions
References
Cellulose and Chitin Nanofibers: Potential Applications on Wound Healing
1 Introduction
2 Process of Wound Healing and Trends in Wound Dressing
3 Cellulose and Cellulose Nanofibers (CNFs)
4 Chitin and Chitin Nanofibers (CNFs)
5 Conclusion
References
Bionanocomposites for In Situ Drug Delivery in Cancer Therapy: Early and Late Evaluations
1 Cancer Outline
2 Drug Delivery for Cancer: General Reflections
3 Bionanocomposites
3.1 How to Choose the Right Polymer
3.2 How to Investigate Polymer-Drug Interactions
3.3 Current Achievements in Bionanocomposites for In Situ Drug Delivery
4 Final Considerations
References
Tumor Microenvironment and Intracellular Signal-Activated Nanocomposites for Anticancer Drug Delivery
1 Introduction
2 Tumor Microenvironment and Intracellular Signal
2.1 The Acidic pH
2.2 The Over-Expressed Enzyme
2.3 The Reductive Environment
2.4 The Hypoxia
2.5 Reactive Oxygen Species
2.6 The ATP Gradient
3 Tumor Microenvironment and Intracellular Signal-Activated Nanocomposites for Anticancer Drug Delivery
3.1 pH-Activated Nanocomposites for Anticancer Drug Delivery
3.2 Enzyme-Activated Nanocomposites for Anticancer Drug Delivery
3.3 Reduction (or GSH)-Activated Nanocomposites for Anticancer Drug Delivery
3.4 Hypoxia-Activated Nanocomposites for Anticancer Drug Delivery
3.5 ROS-Activated Nanocomposites for Anticancer Drug Delivery
3.6 ATP-Activated Nanocomposites for Anticancer Drug Delivery
3.7 Multi-stimuli Activated Nanocomposites for Anticancer Drug Delivery
4 Conclusion and Perspectives
References
Nanocomposites for Cancer Targeted Drug Delivery Therapeutics
1 Introduction
2 Passive and Active Targeting
3 Polymer-Based Nanocomposites
4 Inorganic-Based Nanocomposites
4.1 Clay-Based Nanocomposites
4.2 Metal-Based Nanocomposites
4.3 Silica-Based Nanocomposites
4.4 Magnetic-Based Nanocomposites
4.5 Carbon-Based Nanocomposites
5 Conclusions and Perspectives
References