Biomedical Application of Nanoparticles

✍ Scribed by Bertrand Rihn

• Publisher: CRC Press
• Year: 2018
• Tongue: English
• Leaves: 349
• Series: Oxidative Stress and Disease
• Edition: 1
• Category: Library

✦ Synopsis

This book explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune systems and targeted cells. Risk assessment of nanoparticles for human use is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and, therefore, may enhance drug bioavailability.

✦ Table of Contents

Content: Cover
Half Title
Title Page
Copyright Page
Table of Contents
Foreword
Series Preface: Oxidative Stress in Health and Disease
Editor
Contributors
Section I : Nanoparticle Characterization
Chapter 1: Nanoparticle World
1.1 Introduction
1.2 Nanomedicine
1.3 Diagnostics/Imaging with Nanomaterials
1.4 Nanopharmaceuticals
1.5 Nanoparticle-Based Drug Delivery
1.6 Tissue Engineering with Nanomaterials
1.7 Toxicology of Nanoparticles Used for Medical Purposes
1.8 Conclusion
References
Chapter 2: Dispersion and Characterization of Nanoparticles
2.1 Introduction 2.2 Dispersion of Nanoparticles 2.2.1 Deagglomeration
2.2.2 Stabilization
2.2.2.1 Electrostatic Repulsion
2.2.2.2 Steric Stabilization
2.2.2.3 Electrosteric Stabilization
2.2.2.4 Summary
2.3 Characterization of Nanoparticles Size
2.4 Characterization of Nanoparticles Morphology and Structure
2.5 Physicochemical Characterization of Nanoparticles
2.6 Conclusion
References
Chapter 3: Nanomedicine Clinical and Preclinical Use
3.1 Introduction
3.2 Micro- and Nanoparticulate Delivery Systems
3.2.1 Lipid-Based Nanoparticles
3.2.2 Self-Assembled Nanosystems 3.2.3 Polymeric Micro- and Nanoparticles 3.2.4 Inorganic Nanoparticles
3.2.4.1 Silica Nanoparticles
3.2.4.2 Metal and Metal Oxides Nanoparticles
3.2.5 Carbon Nanocarriers
3.2.5.1 Carbon Nanocapsules and Nanospheres
3.2.5.2 Carbon Nanotubes
3.2.6 Dendrimers
3.2.7 Nanocrystals
3.3 Nanoparticle Use in Therapy
3.3.1 Cancer
3.3.2 Neurodegenerative Diseases
3.3.3 Autoimmune Diseases
3.3.4 Metabolic Disorders
3.3.4.1 Diabetes Mellitus Type 1
3.3.4.2 Lactose Intolerance
3.3.5 Cardiovascular Diseases
3.3.6 Vaccination and Infectious Diseases
3.3.7 Nutrition 3.3.7.1 Curcumin 3.3.7.2 Probiotics
3.4 Nanoparticle Use for Therapeutic and Diagnostic Purposes
3.4.1 Magnetic Nanoparticles
3.4.2 Photosensitizer Nanoparticles
3.4.3 Radiolabeled Nanoparticles
3.4.4 Bi- and Multimodal Nanoparticles
3.4.4.1 MR-Optical Dual-Modality in Vivo Imaging
3.4.4.2 MR-PET Dual-Modality in Vivo Imaging
3.4.4.3 Other Multimodality Imaging
References
Chapter 4: Green Synthesis and Characterization of Semiconductor and Metal Nanoparticles
4.1 Introduction
4.2 Semiconductor Nanoparticles
4.3 Metal Nanoparticles 4.4 Green Synthesis of Nanomaterials 4.5 Characterization Techniques for Nanoparticles
4.5.1 Optical Characterization
4.5.1.1 UV-Vis Spectroscopy
4.5.1.2 Photoluminescence Spectroscopy
4.5.1.3 FT-IR Spectroscopy
4.5.1.4 Raman Spectroscopy
4.5.2 Morphological Characterization
4.5.2.1 X-Ray Diffraction Analysis Studies
4.5.2.2 Dynamic Light Scattering Technique (DLS)
4.5.2.3 Surface Area Analysis (BET)
4.5.2.4 X-Ray Photoelectron Spectroscopy
4.5.2.5 Atomic Force Microscope (AFM)
4.5.2.6 Scanning Electron Microscope (SEM)
4.5.2.7 Transmission Electron Microscope (TEM)

✦ Subjects

Nanoparticles;Nanotechnology -- Methods;Biomedical materials;HEALTH & FITNESS / Holism;HEALTH & FITNESS / Reference;MEDICAL / Alternative Medicine;MEDICAL / Atlases;MEDICAL / Essays;MEDICAL / Family & General Practice;MEDICAL / Holistic Medicine;MEDICAL / Osteopathy;Nanotechnology