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Biomarkers of Intrinsic Angiogenic and Anti-angiogenic Activity in Patients with Endometrial Hyperplasia and Endometrial Cancer

✍ Scribed by Mohamed Shaarawy, Sherif A. El-Shar,


Book ID
121509983
Publisher
Informa plc
Year
2001
Tongue
English
Weight
141 KB
Volume
40
Category
Article
ISSN
0284-186X

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## Background: Hypoxia-inducible factor 1alpha (hif-1alpha) and hif-2alpha are essential regulatory proteins for the adaptation of tumor cells to hypoxia, and they stimulate angiogenesis through activation of the vascular endothelial growth factor (vegf) gene. ## Methods: Hif-1alpha and hif-2alph