Biomarkers of Caloric Restriction May Predict Longevity in Humans
β Scribed by Roth, G. S.
- Book ID
- 118004707
- Publisher
- American Association for the Advancement of Science
- Year
- 2002
- Tongue
- English
- Weight
- 52 KB
- Volume
- 297
- Category
- Article
- ISSN
- 0036-8075
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## Abstract Research on caloric restriction for longevity (CRL) has generated hundreds of articles on the physiology of food deprivation, yet almost no data on consequences in other domains. The first paper in this series outlined the generally positive physical effects of CRL; the second analyses
## Abstract Caloric restriction (CR), which improves health and increases longevity, was studied as a therapy in a hexosaminidase Ξ² knockout mouse model of Sandhoff disease (SD), an incurable neurodegenerative disease involving accumulation of brain ganglioside GM2 and asialoβGM2 (GA2). Adult mice