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Biomarkers in sickle cell disease

✍ Scribed by David C. Rees; John S. Gibson


Book ID
108677515
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
202 KB
Volume
156
Category
Article
ISSN
0007-1048

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Sickle cell anemia and the related hemoglobinopathies are associated with a large spectrum of renal abnormalities. The patients have impaired urinary concentrating ability, defects in urinary acidification and potassium excretion, and supranormal proximal tubular function. The latter is manifest by