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Biomarkers and molecular tumour classification for non-genotoxic carcinogenesis

✍ Scribed by Jonathan Moggs; Roland Wolf; Thomas Friedberg; Neil Stewart; Cliff Elcombe; Simon Plummer; Bettina Grasl-Kraupp; Rolf Schulte-Hermann; Christopher Gerner; Richard Meehan; Michael Schwarz; Andreas Zell; Adrian Schroeder; Jochen Supper; Bernd Pichler; Markus Templin; Patrick Maurel; Martine Daujat-Chavanieu; Jean-Luc Pacquet; Arno Kalkuhl; Katja Matheis; Hans-Juergen Ahr; Stephane Dhalluin; Nina Ostenfeldt

Book ID
119381572
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
63 KB
Volume
189
Category
Article
ISSN
0378-4274

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Transgenic mouse mutation assays: Potent
Transgenic mouse mutation assays: Potential for confusion of genotoxic an non-genotoxic carcinogenesis: A proposed Solution
✍ J. Ashby; U. Leigibel πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 393 KB

The terms genotoxic and non-genotoxic are used increasingly to distinguish rodent carcinogens that are overtly DNA-reactive and mutagenic from those that appear to induce cancer by other mechanisms. There are, however, no universally agreed definitions of these terms . Initial discussions centred on