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Biology of Normal and Acute Myeloid Leukemia Stem Cells

✍ Scribed by John E. Dick; Tsvee Lapidot

Book ID
111835516
Publisher
Carden Jennings Publishing
Year
2005
Tongue
English
Weight
110 KB
Volume
82
Category
Article
ISSN
0925-5710

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## Abstract Chronic Myeloid Leukemia (CML), a myeloproliferative disease of stem cell origin, is characterized by the presence of the Philadelphia (Ph) chromosome and the __bcr‐abl__ oncogene. The BCR‐ABL fusion gene product, thought to be causative in CML, has multiple effects on diverse cell func