Blocking the action of insulin-like growth factor I (IGF I) impairs kidney development in vitro. However, no renal developmental abnormalities have been reported in newborn transgenic mice that do not express IGF I (Igf1 Ϫ/Ϫ ) mice. Ninety-five percent of Igf1 Ϫ/Ϫ mice die immediately following birt
Biology of insulin-like growth factors in development
✍ Scribed by Joëlle Dupont; Martin Holzenberger
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 329 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1542-975X
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