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Biology of EWS/ETS fusions in Ewing's family tumors

โœ Scribed by Arvand, Afsane; Denny, Christopher T


Book ID
110064859
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
247 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract Ewing sarcoma (ES) and peripheral primitive neuroectodermal tumors (PNETs) are associated with a chromosomal translocation resulting in a fusion of the aminoโ€terminus of EWS with the DNAโ€binding domain of an ETS transcription factor (most commonly FLI1 or ERG). Although previous reports