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Biologically Active Metabolites from Fungi, 4. Palmarumycins CP1–CP4 fromConiothyrium palmarum: Isolation, Structure Elucidation, and Biological Activity

✍ Scribed by Krohn, Karsten ;Michel, Andreas ;Flörke, Ulrich ;Aust, Hans-Jürgen ;Draeger, Siegfried ;Schulz, Barbara

Book ID: 102903043
Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 530 KB
Volume: 1994
Category: Article
ISSN: 0947-3440
DOI: 10.1002/jlac.199419941107

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✦ Synopsis

Abstract

Four new penta‐ and hexacyclic antifungal and antibacterial metabolites, the palmarumycins CP~1~–CP~4~ (1–4), were isolated from Coniothyrium palmarum. In these structurally unique antibiotics, a 1,8‐dihydroxynaphthalene unit is connected by a spiroacetal to another partially reduced naphthalene unit. The structure of the pentacyclic palmarumycin CP~3~ (3) was confirmed by X‐ray structure analysis.

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