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Biologically Active Glycosides from Asteroidea, 37. Glycosphingolipids from the StarfishLuidia maculata, 1 Structure of A New Sulfatide Molecular Species

✍ Scribed by Kawatake, Satoshi ;Inagaki, Masanori ;Isobe, Ryuichi ;Miyamoto, Tomofumi ;Higuchi, Ryuichi

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
367 KB
Volume
1997
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

A sulfatide molecular species [LMG‐1 (1)] have been obtained from the water soluble lipid fraction of the chloroform/methanol extract of the starfish Luidia maculata. On the basis of chemical and spectroscopic findings, the structure of 1 has been elucidated. Negative FAB mass spectrometry provided important information both on the structure of the sugar moiety and on the molecular mass of the sulfatide. 1 is, to the authors' knowledge, new sulfatide molecular species and first sulfatide obtained from starfish. In addition, 1 shows neuritogenic activity toward the rat pheochromocytoma cell line, PC‐12 cell.

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