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Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis

✍ Scribed by William A. Carlezon Jr.; Mark J. Thomas

Book ID
116785085
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
420 KB
Volume
56
Category
Article
ISSN
0028-3908

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Previous studies from our laboratory using methylnaloxonium, a hydrophilic antagonist, showed that opiate receptors in the region of the nucleus accumbens are important for the acute reinforcing effects of heroin in non-dependent rats. A similar increased sensitivity to the response disruptive effec