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Biological Sciences: Induction of Hapten-specific B Cell Tolerance by Low Doses of Hapten-Carrier Conjugate

✍ Scribed by TAUSSIG, M. J.


Book ID
109687000
Publisher
Nature Publishing Group
Year
1973
Tongue
English
Weight
346 KB
Volume
245
Category
Article
ISSN
0028-0836

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Effect of prior sensitization with hapte
✍ S. H. Leech; N. A. Mitchison πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 729 KB

## Abstract Mice tolerized by low doses of bovine IgG (BGG), immunized with arsanilated (ARS) conjugates and challenged with ARS‐BGG show an augmented anti‐ BGG antibody response compared with controls immunized with nonconjugated carrier. Conditions optimal for generating hapten help are explored